Gene information
Official symbol MEFV
Official full name MEFV innate immuity regulator, pyrin
Gene type protein-coding gene
Chromosome16p13.3
Alias symbolFMF; TRIM20
Previous symbolMEF
Gene familyTripartite motif containing; Pyrin domain containing
Resources
Entrez Gene 4210
HGNC HGNC:6998
Ensembl ENSG00000103313
Vega OTTHUMG00000129324
UCSC uc002cun.1
GO terms: 31 records
GO Description Category LogP Number of genes Detail
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0002221 pattern recognition receptor signaling pathway GO Biological Processes -6.97185167 18 More
GO:0002764 immune response-regulating signaling pathway GO Biological Processes -3.80325753 14 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0010506 regulation of autophagy GO Biological Processes -5.54010569 34 More
GO:0010508 positive regulation of autophagy GO Biological Processes -4.14985165 17 More
GO:0010950 positive regulation of endopeptidase activity GO Biological Processes -13.2452311 34 More
GO:0010952 positive regulation of peptidase activity GO Biological Processes -14.1524623 37 More
GO:0030027 lamellipodium GO Cellular Components -1.61995196 15 More
GO:0031252 cell leading edge GO Cellular Components -1.97716247 28 More
GO:0031331 positive regulation of cellular catabolic process GO Biological Processes -13.5134767 30 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031348 negative regulation of defense response GO Biological Processes -30.3795513 65 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0032651 regulation of interleukin-1 beta production GO Biological Processes -19.7300517 34 More
GO:0032652 regulation of interleukin-1 production GO Biological Processes -24.2088254 41 More
GO:0032682 negative regulation of chemokine production GO Biological Processes -6.18749803 9 More
GO:0032691 negative regulation of interleukin-1 beta production GO Biological Processes -9.98402343 15 More
GO:0032692 negative regulation of interleukin-1 production GO Biological Processes -11.9554195 18 More
GO:0032695 negative regulation of interleukin-12 production GO Biological Processes -6.32323278 8 More
GO:0034341 response to interferon-gamma GO Biological Processes -10.8524889 26 More
GO:0043254 regulation of protein-containing complex assembly GO Biological Processes -7.63830100 21 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050728 negative regulation of inflammatory response GO Biological Processes -31.0556128 55 More
GO:0051129 negative regulation of cellular component organization GO Biological Processes -13.1016989 75 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0061702 inflammasome complex GO Cellular Components -2.92766476 3 More
GO:0070269 pyroptosis GO Biological Processes -4.13020121 7 More
GO:1900225 regulation of NLRP3 inflammasome complex assembly GO Biological Processes -4.09160195 4 More
GO:2000116 regulation of cysteine-type endopeptidase activity GO Biological Processes -14.4496812 41 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa05135 Yersinia infection KEGG Pathway -7.02427022 12 More
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_000243.3:c.2080A>G genomics acute myocardial infarction[diagnosis] acute myocardial infarction Grimaldi MP et al. J Leukoc Biol. 2006
All rights reserved: Soochow University Center for Systems Biology